Synovial sarcoma occurs in the second through fifth decades, with the average age of incidence around 28 years.
The presentation of synovial sarcoma is variable and may mimic a benign process such as ganglion cyst. The patient may have a mass that has been present for months, years, or even decades, with slow growth and little or no symptoms. There may have been recent rapid growth of a lesion that has been present for years without apparent change. Conversely, some of these sarcomas may be very painful from the outset. The average duration of symptoms before diagnosis is 21 months.
MRI findings are "indeterminate" as defined previously, with intermediate or low signal intensity on T1 sequences and high signal intensity on T2 sequences.
Both chemotherapy and radiotherapy have been shown to have a positive effect on survival.