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51 year old with knee pain

Case Identification
Case ID Number: 
20090721KP
Periosteal Reaction: 
absent
Benign/Malignant: 
unknown
Clinical case information
Case presentation: 

A 51 year old woman presents with left knee pain for 1 year. There has been no previous history of disease, injury, or exposure.

Radiological findings:: 
A lytic lesion is seen in the distal femur. Plain xrays, bone scan, and MRI are performed. Images are shown at left.
Laboratory results:: 
None of significance.
Pathology results:: 
Biopsy results are shown.
Special Features of this Case:: 
This large tumor presents a significant risk of pathological fracture. How should this be addressed?
Image Reference: