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Juxtacortical chondroma


Juxtacortical chondroma (synonym: periosteal chondroma) is a rare benign surface lesion composed of cartilage.

Occurs in in teenages and young adults
A slow growing mass with mild pain or joint symptoms.
Occurs under the periosteum, may have cartilage features.
Curettage is curative
Complete Information on this Tumor
Introduction and Definition: 

Juxtacortical chondroma (synonym: periosteal chondroma) is a rare benign surface lesion composed of cartilage. It is similar in appearance and location to periosteal osteosarcoma. The potential for confusion with periosteal and even parosteal osteosarcoma mandates a thorough investigation and biopsy of these lesions.

Incidence and Demographics: 
Rare. Occurs in the 2nd and 3rd decage, more males than females.
Symptoms and Presentation: 

Mild pain or symptoms arising from the nearby joint.

X-Ray Appearance and Advanced Imaging Findings: 
Radiographically the lesion has its epicenter in the region of the outer cortical surface of the bone. There is no stalk or peduncle as in an osteochondroma. The most common location is adjacent to the metaphysis. The cortex may be involved to a variable degree, but the lesions do not involve the medullary space. There is a mass outside the confines of the bone that contains amorphous ossification. In the cases of this lesion I have seen there were no ring and arc figures seen in the ossified matrix, and neither was there any trace of trabecular organization of the ossified material. There is no periosteal reaction, but the lesion may lift the periosteum and create "columns" or "buttresses" of mature periosteum at each end of the mass that appear to project out from the axis of the bone. Pressure from growth of the lesion may create a saucer shaped or complex shaped defect in the underlying bone. Bone scan will show that the lesion is actively making bone, and is only helpful to count lesions. CT scan shows a more precise picture of the lesion and its juxtacortical location. It may reveal the amorphous character of the ossific material within the lesion, as well as help in distinguishing the tumor from osteochondroma, osteoid osteoma, and myositis ossificans, but not from periosteal osteosarcoma and parosteal osteosarcoma. CT should be done even if an MRI has been done. MRI is not likely to be of much additional value after CT. If doubt exists about the nature of the tissue in the lesion the MRI may help identify the cartilage component.
Laboratory Findings: 
Laboratory exam will help only in confirming that there is no systemic condition such as infection.
Differential Diagnosis: 
To differential the lesion from the surface osteosarcomas, look for a mass of very heavily ossified tumor bone plastered in the surface of the bone. Periosteal osetosarcoma tends to be more diaphyseal, a little less ossified, and has a more rapid growth pattern as compared to juxtacortical chondroma. I myself would not feel confident making a call of juxtacortical chondroma based on imaging alone, most cases will require a careful biopsy, making sure the lesion is fully sampled.
Preferred Biopsy Technique for this Tumor: 
Open, may be excisional if diagnosis is certain.
Histopathology findings: 
On gross pathology, the lesion consists of cartilage and ossified cartilage. On microscopic exam there is benign cartilage with typical chondrocytes in scattered lacunae and noneoplastic bone being formed by enchondral ossification. There is no neoplastic cartilage with hypercellularity or bizarre chondrocytes, and no neoplastic osteoid or bone as in periosteal osteosarcoma.
Treatment Options for this Tumor: 
Preferred Margin for this Tumor: 
Outcomes of Treatment and Prognosis: 
Usually excellent.